CD33 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: CD33 molecule
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 67 kDa
Uniprot: P20138
Gene id: 945
Background: Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia(in vitro).
Field of research: Neuroscience, Stem Cells, Immunology, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IF
Dilution: WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Target: CD33
Purification: Immunogen affinity purified
Reactivity: Human
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: CD33 molecule
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 67 kDa
Uniprot: P20138
Gene id: 945
Background: Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia(in vitro).
Field of research: Neuroscience, Stem Cells, Immunology, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IF
Dilution: WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Target: CD33
Purification: Immunogen affinity purified
Reactivity: Human